STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD11B1LHydroxysteroid 11-beta dehydrogenase 1 like. (302 aa)    
Predicted Functional Partners:
CYP21A2
Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
   
 0.920
LOC101089816
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.920
CYP2E2
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.920
LOC101089561
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.920
LOC101097790
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 
 0.919
HSD11B2
Hydroxysteroid 11-beta dehydrogenase 2.
   
 
 0.917
AKR1D1
Aldo-keto reductase family 1 member D1.
   
 
 0.914
HSD11B1
Hydroxysteroid 11-beta dehydrogenase 1.
  
0.913
HSD3B2
3 beta-hydroxysteroid dehydrogenase; Belongs to the 3-beta-HSD family.
   
 0.906
UGT1A
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
    
 0.905
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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