STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)    
Predicted Functional Partners:
ACO2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.998
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
  
 0.997
MDH2
Malate dehydrogenase, mitochondrial; Belongs to the LDH/MDH superfamily. MDH type 1 family.
  
 0.996
ACLY
ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
  
 0.994
DLAT
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.990
SDHB
Succinate dehydrogenase complex iron sulfur subunit B.
  
 0.986
MDH1
Malate dehydrogenase, cytoplasmic.
  
 0.982
ACSS2
Acyl-CoA synthetase short chain family member 2.
  
 0.978
FH
Fumarate hydratase.
  
 0.978
ACSS1
Acetyl-coenzyme A synthetase.
  
 0.978
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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