STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL23AInterleukin 23 subunit alpha. (196 aa)    
Predicted Functional Partners:
IL23R
Interleukin 23 receptor.
   
 0.995
IL12RB1
Interleukin 12 receptor subunit beta 1.
    
 0.985
TYK2
Tyrosine-protein kinase.
     
 0.953
JAK2
Tyrosine-protein kinase.
     
 0.952
IL4R
Interleukin 4 receptor.
  
  
 0.774
IL12RB2
Interleukin 12 receptor subunit beta 2.
   
 
 0.744
IL22RA1
Interleukin 22 receptor subunit alpha 1.
  
  
 0.740
IL10RA
Interleukin 10 receptor subunit alpha.
  
  
 0.733
IL20RA
Interleukin 20 receptor subunit alpha.
  
  
  0.720
IL13RA1
Interleukin 13 receptor subunit alpha 1.
  
  
  0.720
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.