Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNRF1Zinc and ring finger 1. (227 aa)    
Predicted Functional Partners:
UBE2N
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.745
ENSFCAP00000034079
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 
 0.745
ENSFCAP00000034335
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 
 0.745
UBE2D1
Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
   
 
 0.688
ENSFCAP00000026617
Ubiquitin-like domain-containing protein.
   
  0.674
ALLC
Allantoicase.
      
 0.665
SARM1
Sterile alpha and TIR motif containing 1.
      
 0.649
ARRDC5
Arrestin domain containing 5.
      
 0.633
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
      
 0.610
VGLL4
Vestigial like family member 4.
      
 0.595
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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