STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PATL2SPG11 vesicle trafficking associated, spatacsin. (2444 aa)    
Predicted Functional Partners:
AP5Z1
Adaptor related protein complex 5 subunit zeta 1.
    
 
 0.928
ZFYVE26
Zinc finger FYVE-type containing 26.
   
 
 0.918
SPG21
SPG21 abhydrolase domain containing, maspardin.
      
 0.836
SUSD1
Sushi domain containing 1.
      
 0.759
DSTYK
Dual serine/threonine and tyrosine protein kinase.
      
 0.745
PRAF2
WD repeat domain 45.
      
 0.713
RNF130
TBC1 domain family member 9B.
      
 0.683
NIPA1
NIPA magnesium transporter 1.
      
 0.668
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
      
 0.668
AP5M1
Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.
    
 
 0.667
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.