Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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[Homology]
Score
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)    
Predicted Functional Partners:
AGL
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase.
  
 0.990
GBE1
1,4-alpha-glucan-branching enzyme; Required for normal glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 0.979
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.954
PHKG1
Phosphorylase kinase catalytic subunit gamma 1; Belongs to the protein kinase superfamily.
   
 0.932
AMY2B
Alpha-amylase.
  
 0.928
PGM2
Phosphoglucomutase 2.
  
 
 0.917
PGM2L1
Phosphoglucomutase 2 like 1.
  
 
 0.917
PHKA2
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.
   
 
 0.916
PGM5
Phosphoglucomutase 5; Belongs to the phosphohexose mutase family.
  
 
 0.913
PHKG2
Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily.
   
 0.912
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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