STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (594 aa)    
Predicted Functional Partners:
INSR
Tyrosine-protein kinase receptor.
    
 0.986
IGF1R
Tyrosine-protein kinase receptor.
    
 0.984
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.951
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.921
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
     
 0.914
NEDD4
NEDD4 E3 ubiquitin protein ligase.
    
 
 0.877
PLAG1
PLAG1 zinc finger.
    
 0.785
ENSFCAP00000044386
Uncharacterized protein.
     
 0.774
GPC3
Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
   
  
 0.768
GIGYF2
GRB10 interacting GYF protein 2.
    
 
 0.768
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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