STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NLRC3NLR family CARD domain containing 3. (1060 aa)    
Predicted Functional Partners:
ZDHHC1
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.769
RNF5
Ring finger protein 5.
   
  
 0.697
NLRC4
NLR family CARD domain containing 4.
   
 
 0.653
TRIM56
Tripartite motif containing 56.
   
 0.631
AMFR
Autocrine motility factor receptor.
    
 
 0.596
NAIP
NACHT domain-containing protein.
    
 0.570
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.527
CLEC2L
C-type lectin domain family 2 member L.
      
 0.485
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.476
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
   
 0.471
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.