STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)    
Predicted Functional Partners:
TP53INP1
Tumor protein p53 inducible nuclear protein 1.
      
 0.606
CABP1
Calcium binding protein 1.
    
 
 0.580
OTOP3
Otopetrin 3.
      
 0.517
RENBP
Renin binding protein.
      
 0.504
TRIB3
Tribbles pseudokinase 3.
   
  
 0.480
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
    
 
 0.470
TCF20
Transcription factor 20.
    
 
 0.461
TXNDC17
Thioredoxin domain containing 17.
      
 0.455
PNPLA8
Patatin like phospholipase domain containing 8.
      
 0.455
TP53INP2
Tumor protein p53 inducible nuclear protein 2.
      
 0.455
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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