STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RALGPS2Ral GEF with PH domain and SH3 binding motif 2. (583 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
   
 0.796
ENSFCAP00000028128
Uncharacterized protein.
      
 0.752
ASTN1
Astrotactin 1.
   
 0.714
ESRP2
Epithelial splicing regulatory protein 2.
      
 0.671
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 
 0.618
RALB
RAS like proto-oncogene B.
    
 0.617
TIMM17A
Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
   
  
 0.617
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.613
EEF1AKNMT
EEF1A lysine and N-terminal methyltransferase.
      
 0.612
MEF2C
MADS-box domain-containing protein.
   
  
 0.581
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (20%) [HD]