Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFF4AF4/FMR2 family member 4. (1197 aa)    
Predicted Functional Partners:
CCNT1
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.998
CDK9
Cyclin dependent kinase 9; Belongs to the protein kinase superfamily.
    
 0.997
CCNT2
Cyclin T2; Belongs to the cyclin family.
   
 0.997
ELL
Elongation factor for RNA polymerase II.
    
 0.996
ELL3
Elongation factor for RNA polymerase II 3.
    
 0.995
EAF2
ELL associated factor 2.
    
 0.993
EAF1
ELL associated factor 1.
    
 0.993
ELL2
Elongation factor for RNA polymerase II 2.
    
 0.988
MLLT1
MLLT1 super elongation complex subunit.
    
 0.974
LOC101091265
Uncharacterized protein.
    
 0.974
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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