Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NPATNuclear protein, coactivator of histone transcription. (1442 aa)    
Predicted Functional Partners:
HINFP
Histone H4 transcription factor.
    
 
 0.862
CRAMP1
Cramped chromatin regulator homolog 1.
    
 
 0.828
CCNE1
Cyclin E1; Belongs to the cyclin family.
    
 
 0.824
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.780
ZNF219
Zinc finger protein 219.
    
  0.741
CASP8AP2
Caspase 8 associated protein 2.
   
 
 0.667
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
    
 
 0.653
IQCB1
IQ motif containing B1.
   
 
 0.635
CCNE2
Cyclin E2; Belongs to the cyclin family.
    
 
 0.621
HCCS
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
    
 
 0.620
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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