Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa)    
Predicted Functional Partners:
PANX1
Pannexin; Structural component of the gap junctions and the hemichannels.
     
 0.903
P2RX5
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
   
 0.834
P2RX1
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.827
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
     
  0.797
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
     
 0.767
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
     
 0.767
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
     
 0.630
CHRNA7
Uncharacterized protein.
     
 0.621
P2RX4
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
     
 0.594
ENSFCAP00000058240
Uncharacterized protein.
  
  
0.587
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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