Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAP1Adenylyl cyclase-associated protein; Belongs to the CAP family. (475 aa)    
Predicted Functional Partners:
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
   0.927
CFL1
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.884
ENSFCAP00000047404
Uncharacterized protein.
   
 0.884
WDR1
WD repeat domain 1.
   
 
 0.848
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
    
   0.830
TWF2
Twinfilin actin binding protein 2.
   
 
 0.811
TWF1
Twinfilin actin binding protein 1.
   
 
 0.811
BCL7C
BAF chromatin remodeling complex subunit BCL7C.
    
   0.810
PFN4
Profilin; Belongs to the profilin family.
   
 0.759
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.728
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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