Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TPM2Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)    
Predicted Functional Partners:
TNNI1
Troponin I1, slow skeletal type.
   
 0.900
TNNT3
Troponin T3, fast skeletal type.
   
 0.800
ACTC1
Actin alpha cardiac muscle 1.
   
 0.791
MYL1
Myosin light chain 1.
   
 0.737
TPM4
Tropomyosin 4; Belongs to the tropomyosin family.
     
  0.702
TNNT1
Troponin T1, slow skeletal type.
   
 0.702
TNNT2
Troponin T2, cardiac type.
   
 0.702
ACTN2
Actinin alpha 2.
   
 0.683
ACTA1
Actin alpha 1, skeletal muscle.
   
 0.664
TMOD1
Tropomodulin 1.
   
 0.642
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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