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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYRO3TYRO3 protein tyrosine kinase. (889 aa)    
Predicted Functional Partners:
GAS6
Growth arrest specific 6.
    
 0.594
DIXDC1
DIX domain containing 1.
    
 
 0.579
COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.
      
 0.578
PROS1
Protein S.
     
 0.578
CAMTA1
Calmodulin binding transcription activator 1.
      
 0.578
CD209
C-type lectin domain-containing protein.
    
 0.546
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.534
SOCS1
Suppressor of cytokine signaling 1.
    
 0.497
ITSN2
Intersectin 2.
   
 0.474
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.469
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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