STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DGKQDiacylglycerol kinase. (942 aa)    
Predicted Functional Partners:
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
     
  0.900
GNPAT
Dihydroxyacetone phosphate acyltransferase.
     
 0.840
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4.
     
 0.830
MBOAT1
Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family.
     
 0.821
LCLAT1
Lysocardiolipin acyltransferase 1.
     
 0.820
GPD2
Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
  0.814
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3.
     
 0.812
PLCE1
Phosphoinositide phospholipase C.
     
 0.770
GPD1L
Glycerol-3-phosphate dehydrogenase [NAD(+)].
     
 0.722
PLCD4
Phosphoinositide phospholipase C.
     
 0.721
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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