Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TET1Tet methylcytosine dioxygenase 1. (2142 aa)    
Predicted Functional Partners:
DNMT1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.813
ARID4B
AT-rich interaction domain 4B.
   
 
 0.738
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase.
   
 
 0.719
TDG
Thymine DNA glycosylase.
      
 0.654
NANOG
Nanog homeobox.
   
 
 0.643
LOC101084379
Homeobox domain-containing protein.
   
 
 0.643
ENSFCAP00000037965
Homeobox domain-containing protein.
   
 
 0.643
DCAF1
DDB1 and CUL4 associated factor 1.
    
 
 0.637
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 
 0.636
SUDS3
SDS3 homolog, SIN3A corepressor complex component.
    
   0.611
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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