STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111559090Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (129 aa)    
Predicted Functional Partners:
APOA1
Apolipoprotein A1.
     
 0.549
APOM
Apolipoprotein M.
     
 0.541
APOC4
Uncharacterized protein.
     
  0.540
LIPG
Lipase G, endothelial type.
     
  0.540
NR1I3
Nuclear receptor subfamily 1 group I member 3.
     
  0.540
APOC2
Uncharacterized protein.
     
  0.540
APOC3
Apolipoprotein C3.
     
  0.540
APOB
Apolipoprotein B.
     
  0.540
APOC1
Truncated apolipoprotein C-I; Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the in [...]
     
  0.540
APOA5
Apolipoprotein A5.
     
  0.540
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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