STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCG1ATP binding cassette subfamily G member 1. (678 aa)    
Predicted Functional Partners:
APOA1
Apolipoprotein A1.
   
 0.816
ABCG5
ATP binding cassette subfamily G member 5.
   
0.800
SCARB1
Scavenger receptor class B member 1; Belongs to the CD36 family.
   
  
 0.730
NR1H3
Nuclear receptor subfamily 1 group H member 3.
   
 0.678
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.609
CROT
Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
  
 0.600
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
   
 0.599
ABCC1
ATP binding cassette subfamily C member 1.
   
 0.594
SULT2B1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.560
NPC1
NPC intracellular cholesterol transporter 1.
   
 
 0.553
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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