STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa)    
Predicted Functional Partners:
MAP2K7
Mitogen-activated protein kinase kinase 7.
    
0.925
AKAP7
A-kinase anchoring protein 7.
      
 0.810
EPB41L2
Erythrocyte membrane protein band 4.1 like 2.
      
 0.769
AHCYL2
Adenosylhomocysteinase like 2; Belongs to the adenosylhomocysteinase family.
      
 0.631
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
      
 0.630
RASA2
RAS p21 protein activator 2.
   
  
 0.603
TAFA1
TAFA chemokine like family member 1.
      
 0.577
GSE1
Gse1 coiled-coil protein.
      
 0.577
MYCBP2
MYC binding protein 2.
    
 
 0.528
EPB41L5
Erythrocyte membrane protein band 4.1 like 5.
      
 0.525
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: medium (42%) [HD]