Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PYROXD1Pyridine nucleotide-disulphide oxidoreductase domain 1. (502 aa)    
Predicted Functional Partners:
UPRT
Uracil phosphoribosyltransferase homolog.
  
   0.928
FADS6
Fatty acid desaturase 6.
   
 0.882
RTCB
RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
   
 
 0.822
MCHR1
Melanin concentrating hormone receptor 1.
      
 0.740
LSM2
U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
   0.713
MRPS35
Mitochondrial ribosomal protein S35.
   
 
 0.661
RECQL
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
     
 0.650
TMEM184C
Transmembrane protein 184C.
      
 0.644
SUOX
Sulfite oxidase.
   
 0.631
ADRM1
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.584
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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