Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
VSIRV-set immunoregulatory receptor. (311 aa)    
Predicted Functional Partners:
IGSF11
Immunoglobulin superfamily member 11.
     
 0.923
AARS1
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.
      
 0.542
STKLD1
Serine/threonine kinase like domain containing 1.
      
 0.539
LAG3
Lymphocyte activating 3.
      
 0.506
VWA8
Von Willebrand factor A domain containing 8.
      
 0.504
TRMT61B
tRNA methyltransferase 61B.
      
 0.501
HVCN1
Hydrogen voltage gated channel 1.
      
 0.483
PDCD1
Programmed cell death 1.
      
 0.447
CTLA4
Cytotoxic T-lymphocyte associated protein 4.
      
 0.444
FAAP24
FA core complex associated protein 24.
      
 0.443
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (16%) [HD]