Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXO10F-box protein 10. (956 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.969
ENSFCAP00000055272
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.825
SKP1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.825
ACSL4
Acyl-CoA synthetase long chain family member 4.
   
 
 0.791
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.708
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 
 0.649
RCBTB2
RCC1 and BTB domain containing protein 2.
      
 0.647
FRMPD1
FERM and PDZ domain containing 1.
    
 
 0.617
RBX1
Ring-box 1.
    
 0.588
ACSL3
Acyl-CoA synthetase long chain family member 3.
   
 
 0.578
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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