Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TMEM183ATransmembrane protein 183A. (376 aa)    
Predicted Functional Partners:
NUS1
NUS1 dehydrodolichyl diphosphate synthase subunit.
   
  
 0.840
BMPR1A
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
      
 0.745
TUBGCP2
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
    
 
 0.725
UHRF1
Ubiquitin like with PHD and ring finger domains 1.
   
 
 0.705
PCMT1
Protein-L-isoaspartate O-methyltransferase.
      
 0.633
HSF2BP
Heat shock transcription factor 2 binding protein.
      
 0.597
TTC7B
Tetratricopeptide repeat domain 7B.
      
 0.581
TMEM47
Transmembrane protein 47.
   
  
 0.557
ARIH2
RBR-type E3 ubiquitin transferase.
      
 0.539
AK4
Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
      
 0.532
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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