Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALOX5Arachidonate 5-lipoxygenase. (745 aa)    
Predicted Functional Partners:
COTL1
ADF-H domain-containing protein.
    
 
 0.969
ALOX5AP
Arachidonate 5-lipoxygenase activating protein.
   
 0.968
LTA4H
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
     
 0.962
LTC4S
Leukotriene C4 synthase.
   
 0.954
MAPKAPK2
MAPK activated protein kinase 2.
    
 0.949
PTGS2
Prostaglandin-endoperoxide synthase 2.
   
 
 0.941
MRRF
Prostaglandin-endoperoxide synthase 1.
   
 
 0.934
PLA2G4A
Phospholipase A2.
    
 0.914
LOC101083342
Phospholipase A2.
    
 0.907
PLA2G2F
Phospholipase A(2).
    
 0.907
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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