Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TLL1Metalloendopeptidase. (1012 aa)    
Predicted Functional Partners:
PCOLCE
Procollagen C-endopeptidase enhancer.
   
 0.767
CHRD
Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
   
 
 0.765
MME
Membrane metalloendopeptidase.
     
 0.624
PCOLCE2
Procollagen C-endopeptidase enhancer 2.
   
 0.606
MMEL1
Membrane metalloendopeptidase like 1.
     
 0.580
DCN
Decorin; May affect the rate of fibrils formation.
    
 0.567
IDE
Insulin degrading enzyme.
   
  
 0.553
COL3A1
Collagen type III alpha 1 chain.
   
 0.501
LOXL4
Lysyl oxidase like 4.
   
 0.487
GDF11
Growth differentiation factor 11.
    
 
 0.483
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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