SORL1 protein (Felis catus) - STRING interaction network

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Score

SORL1

Sortilin related receptor 1. (2211 aa)

Predicted Functional Partners:

APP

0.991

LRPAP1

0.950

GGA1

0.870

GAK

0.830

NGFR

0.825

APLP2

0.817

VPS35

0.813

GGA2

0.804

APOB

0.795

CD2AP

0.774

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLP2	APOB	ENSFCAP00000008808	ENSFCAP00000023369	Amyloid beta precursor like protein 2.	Apolipoprotein B.	0.464
APLP2	APP	ENSFCAP00000008808	ENSFCAP00000001445	Amyloid beta precursor like protein 2.	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	0.974
APLP2	NGFR	ENSFCAP00000008808	ENSFCAP00000044299	Amyloid beta precursor like protein 2.	Nerve growth factor receptor.	0.677
APLP2	SORL1	ENSFCAP00000008808	ENSFCAP00000012262	Amyloid beta precursor like protein 2.	Sortilin related receptor 1.	0.817
APOB	APLP2	ENSFCAP00000023369	ENSFCAP00000008808	Apolipoprotein B.	Amyloid beta precursor like protein 2.	0.464
APOB	APP	ENSFCAP00000023369	ENSFCAP00000001445	Apolipoprotein B.	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	0.677
APOB	SORL1	ENSFCAP00000023369	ENSFCAP00000012262	Apolipoprotein B.	Sortilin related receptor 1.	0.795
APP	APLP2	ENSFCAP00000001445	ENSFCAP00000008808	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Amyloid beta precursor like protein 2.	0.974
APP	APOB	ENSFCAP00000001445	ENSFCAP00000023369	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Apolipoprotein B.	0.677
APP	GGA1	ENSFCAP00000001445	ENSFCAP00000043860	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.443
APP	NGFR	ENSFCAP00000001445	ENSFCAP00000044299	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Nerve growth factor receptor.	0.872
APP	SORL1	ENSFCAP00000001445	ENSFCAP00000012262	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	Sortilin related receptor 1.	0.991
CD2AP	SORL1	ENSFCAP00000024327	ENSFCAP00000012262	CD2 associated protein.	Sortilin related receptor 1.	0.774
GAK	SORL1	ENSFCAP00000007628	ENSFCAP00000012262	Cyclin G associated kinase.	Sortilin related receptor 1.	0.830
GAK	VPS35	ENSFCAP00000007628	ENSFCAP00000038222	Cyclin G associated kinase.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.664
GGA1	APP	ENSFCAP00000043860	ENSFCAP00000001445	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...]	0.443
GGA1	GGA2	ENSFCAP00000043860	ENSFCAP00000004799	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.982
GGA1	SORL1	ENSFCAP00000043860	ENSFCAP00000012262	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Sortilin related receptor 1.	0.870
GGA2	GGA1	ENSFCAP00000004799	ENSFCAP00000043860	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.982
GGA2	SORL1	ENSFCAP00000004799	ENSFCAP00000012262	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	Sortilin related receptor 1.	0.804