Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CRYGNCrystallin gamma N; Belongs to the beta/gamma-crystallin family. (183 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
    
 0.920
TSC1
TSC complex subunit 1.
    
 0.841
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.812
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.767
TBC1D7
TBC1 domain family member 7.
     
 0.760
AKT1S1
AKT1 substrate 1.
    
 0.723
MLST8
MTOR associated protein, LST8 homolog.
    
 0.711
BNIP3
BCL2 interacting protein 3.
    
 0.706
DEPTOR
DEP domain containing MTOR interacting protein.
    
 0.659
RPS6KB1
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
    
 0.624
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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