Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (166 aa)    
Predicted Functional Partners:
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
  0.986
LIMK1
LIM domain kinase 1.
   
 0.985
LIMK2
LIM domain kinase 2.
   
 0.968
SSH1
Slingshot protein phosphatase 1.
    
 0.963
SSH3
Slingshot protein phosphatase 3.
    
 0.930
SSH2
Slingshot protein phosphatase 2.
    
 0.925
DSTN
Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
  0.886
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.884
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.871
WDR1
WD repeat domain 1.
   
 
 0.862
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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