STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (166 aa)    
Predicted Functional Partners:
LIMK1
LIM domain kinase 1.
   
 0.995
LIMK2
LIM domain kinase 2.
   
 0.986
SSH1
Slingshot protein phosphatase 1.
    
 0.961
ACTG1
Actin gamma 1.
   
 0.945
SSH2
Slingshot protein phosphatase 2.
    
 0.940
SSH3
Slingshot protein phosphatase 3.
    
 0.940
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
  
 
0.931
CTTN
Cortactin.
   
 
 0.829
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
   
 
 0.828
WDR1
WD repeat domain 1.
   
 
 0.800
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.