Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
UCK1PRK domain-containing protein. (401 aa)    
Predicted Functional Partners:
UPRT
Uracil phosphoribosyltransferase homolog.
 
 0.992
UCK2
Uridine-cytidine kinase; Belongs to the uridine kinase family.
   
  0.990
UPP1
Uridine phosphorylase 1.
    
 0.968
UCKL1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 0.961
CDA
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.951
UMPS
Uridine monophosphate synthetase.
   
 0.950
CMPK1
UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
   
 
 0.937
NT5C
5', 3'-nucleotidase, cytosolic.
    
 0.927
NT5M
5',3'-nucleotidase, mitochondrial.
    
 0.920
ASMTL
Acetylserotonin O-methyltransferase like.
  
 
 0.919
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (20%) [HD]