Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (966 aa)    
Predicted Functional Partners:
ACAN
Aggrecan.
    
 0.658
SLC5A8
Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.623
PIK3R3
Uncharacterized protein.
      
 0.614
USF2
Upstream transcription factor 2, c-fos interacting.
    
 
 0.613
RARRES2
Retinoic acid receptor responder 2.
      
 0.583
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4.
    
 0.581
MMP24
Matrix metallopeptidase 24.
    
 
 0.579
RSPO1
R-spondin 1.
      
 0.579
RUSC2
RUN and SH3 domain containing 2.
      
 0.561
GALNT3
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.561
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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