Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADALAdenosine deaminase like. (356 aa)    
Predicted Functional Partners:
APRT
Adenine phosphoribosyltransferase.
   
 0.791
EPHX2
Epoxide hydrolase 2.
  
 
 0.731
ADK
Adenosine kinase.
   
 0.673
CUL1
Cullin 1; Belongs to the cullin family.
   
 
 0.660
TM2D3
TM2 domain containing 3.
 
    
 0.647
AK9
Uncharacterized protein.
   
 
 0.628
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
 0.607
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.606
PHKB
Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.
      
 0.585
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.
      
 0.584
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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