STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TICRRTOPBP1 interacting checkpoint and replication regulator. (1884 aa)    
Predicted Functional Partners:
TOPBP1
DNA topoisomerase II binding protein 1.
    
 
 0.888
EXO1
Exonuclease 1.
  
 
 0.785
FBL
Fibrillarin.
   
 
 0.771
VWA5B2
Von Willebrand factor A domain containing 5B2.
      
 0.760
CLBA1
Clathrin_bdg domain-containing protein.
      
 0.760
LRWD1
Leucine rich repeats and WD repeat domain containing 1.
   
 
 0.755
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.747
KIF2B
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.732
MTBP
MDM2 binding protein.
   
 0.724
TBL3
Transducin beta like 3.
   
 
 0.710
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.