Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
ARHGEF16Rho guanine nucleotide exchange factor 16. (950 aa)    
Predicted Functional Partners:
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
   0.779
GPR153
G protein-coupled receptor 153.
   
  
 0.767
ACOT7
Acyl-CoA thioesterase 7.
      
 0.757
WRAP73
WD repeat containing, antisense to TP73.
      
 0.754
TPRG1L
Tumor protein p63 regulated 1 like.
      
 0.746
DDX51
DEAD-box helicase 51; Belongs to the DEAD box helicase family.
      
 0.719
RAD21L1
RAD21 cohesin complex component like 1.
      
 0.717
RER1
Retention in endoplasmic reticulum sorting receptor 1.
      
 0.700
ALS2
Alsin Rho guanine nucleotide exchange factor ALS2.
    
 
 0.691
PPIH
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
      
 0.691
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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