SPATA5 protein (Felis catus) - STRING interaction network

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Score

SPATA5

Spermatogenesis associated 5. (935 aa)

Predicted Functional Partners:

UBXN7

0.962

UFD1

0.868

DERL1

0.857

ATXN3

0.847

UBXN6

0.837

PSMD2

0.833

UBXN1

0.830

UBXN4

0.824

NGLY1

0.806

NSFL1C

0.802

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN3	SPATA5	ENSFCAP00000017509	ENSFCAP00000012554	Josephin domain-containing protein.	Spermatogenesis associated 5.	0.847
DERL1	NGLY1	ENSFCAP00000023495	ENSFCAP00000041321	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	N-glycanase 1.	0.952
DERL1	NSFL1C	ENSFCAP00000023495	ENSFCAP00000053730	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NSFL1 cofactor.	0.733
DERL1	PSMD2	ENSFCAP00000023495	ENSFCAP00000007217	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.442
DERL1	SPATA5	ENSFCAP00000023495	ENSFCAP00000012554	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Spermatogenesis associated 5.	0.857
DERL1	UBXN1	ENSFCAP00000023495	ENSFCAP00000008218	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain protein 1.	0.953
DERL1	UFD1	ENSFCAP00000023495	ENSFCAP00000003962	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin recognition factor in ER associated degradation 1.	0.867
NGLY1	DERL1	ENSFCAP00000041321	ENSFCAP00000023495	N-glycanase 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.952
NGLY1	NSFL1C	ENSFCAP00000041321	ENSFCAP00000053730	N-glycanase 1.	NSFL1 cofactor.	0.811
NGLY1	SPATA5	ENSFCAP00000041321	ENSFCAP00000012554	N-glycanase 1.	Spermatogenesis associated 5.	0.806
NGLY1	UBXN1	ENSFCAP00000041321	ENSFCAP00000008218	N-glycanase 1.	UBX domain protein 1.	0.941
NSFL1C	DERL1	ENSFCAP00000053730	ENSFCAP00000023495	NSFL1 cofactor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.733
NSFL1C	NGLY1	ENSFCAP00000053730	ENSFCAP00000041321	NSFL1 cofactor.	N-glycanase 1.	0.811
NSFL1C	SPATA5	ENSFCAP00000053730	ENSFCAP00000012554	NSFL1 cofactor.	Spermatogenesis associated 5.	0.802
NSFL1C	UBXN1	ENSFCAP00000053730	ENSFCAP00000008218	NSFL1 cofactor.	UBX domain protein 1.	0.960
NSFL1C	UBXN4	ENSFCAP00000053730	ENSFCAP00000021442	NSFL1 cofactor.	UBX domain protein 4.	0.935
NSFL1C	UBXN6	ENSFCAP00000053730	ENSFCAP00000048346	NSFL1 cofactor.	UBX domain protein 6.	0.995
NSFL1C	UBXN7	ENSFCAP00000053730	ENSFCAP00000007087	NSFL1 cofactor.	UBX domain-containing protein.	0.954
NSFL1C	UFD1	ENSFCAP00000053730	ENSFCAP00000003962	NSFL1 cofactor.	Ubiquitin recognition factor in ER associated degradation 1.	0.973
PSMD2	DERL1	ENSFCAP00000007217	ENSFCAP00000023495	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.442