STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)    
Predicted Functional Partners:
BECN1
Beclin 1.
    
 0.999
ATG14
Autophagy related 14.
     
 0.997
PIK3R4
Phosphoinositide-3-kinase regulatory subunit 4.
   
 
 0.992
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.990
ULK2
Unc-51 like autophagy activating kinase 2.
   
 0.979
ULK1
Unc-51 like autophagy activating kinase 1.
   
 0.976
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.966
PRKN
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
    
 0.955
UVRAG
UV radiation resistance associated.
      
 0.947
NRBF2
Nuclear receptor binding factor 2.
     
 0.943
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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