Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PRPF19Pre-mRNA processing factor 19. (504 aa)    
Predicted Functional Partners:
CDC5L
Cell division cycle 5 like.
   
 0.997
XAB2
XPA binding protein 2.
   
 0.997
BCAS2
BCAS2 pre-mRNA processing factor.
   
 0.996
PLRG1
Pleiotropic regulator 1.
   
 0.996
AQR
RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
    
 0.995
CTNNBL1
Catenin beta like 1.
   
 0.995
CWC15
CWC15 spliceosome associated protein homolog.
    
 0.989
ISY1
Uncharacterized protein.
    
 0.983
SLU7
SLU7 homolog, splicing factor.
    
 
 0.973
PRPF8
Pre-mRNA processing factor 8.
   
 
 0.965
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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