Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (211 aa)    
Predicted Functional Partners:
TSC2
TSC complex subunit 2.
    
 0.853
TSC1
TSC complex subunit 1.
    
 0.841
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 0.812
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
 
 0.796
CRYBB1
Crystallin beta B1; Belongs to the beta/gamma-crystallin family.
   
   0.781
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.767
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
   
 
 0.738
AKT1S1
AKT1 substrate 1.
    
 0.723
BNIP3
BCL2 interacting protein 3.
    
 0.706
MLST8
MTOR associated protein, LST8 homolog.
    
 0.694
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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