STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRYBB2Crystallin beta B2; Belongs to the beta/gamma-crystallin family. (205 aa)    
Predicted Functional Partners:
CRYAB
Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
   
 
 0.962
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
   
 
 0.954
GJA8
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.771
CRYBA4
Crystallin beta A4; Belongs to the beta/gamma-crystallin family.
   
 
 0.766
BFSP2
Beaded filament structural protein 2; Belongs to the intermediate filament family.
   
  
 0.718
OPN1SW
Opsin 1, short wave sensitive.
      
 0.669
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
      
 0.666
SAG
S-antigen visual arrestin.
   
  
 0.657
CRYBA1
Crystallin beta A1; Belongs to the beta/gamma-crystallin family.
   
 
 0.650
CRYGS
Crystallin gamma S; Belongs to the beta/gamma-crystallin family.
   
 
 0.622
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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