Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM176BTransmembrane protein 176B. (347 aa)    
Predicted Functional Partners:
TMEM176A
Transmembrane protein 176A.
   
 
0.990
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
   
  
 0.613
ABCB8
ATP binding cassette subfamily B member 8.
    
 
 0.609
MTREX
Mtr4 exosome RNA helicase.
   
 0.571
FKBP11
Peptidylprolyl isomerase.
   
 
 0.550
TMSB10
Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family.
      
 0.494
SAMD10
Sterile alpha motif domain containing 10.
      
 0.474
ALKBH7
AlkB homolog 7.
      
 0.443
ENSFCAP00000040083
Uncharacterized protein.
    
 
 0.439
CPXM1
Carboxypeptidase X, M14 family member 1.
      
 0.410
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (10%) [HD]