Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPTSSBSerine palmitoyltransferase small subunit B. (76 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
    
 0.978
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
    
 0.946
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
    
 0.946
SPTSSA
Serine palmitoyltransferase small subunit A.
     
 0.924
ISM1
Isthmin 1.
    
 0.701
LCLAT1
Lysocardiolipin acyltransferase 1.
      
 0.538
MSMP
Beta-microseminoprotein.
      
 0.535
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.534
ISM2
Isthmin 2.
    
 0.525
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.
      
 0.485
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
Server load: low (18%) [HD]