Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CIARTCircadian associated repressor of transcription. (385 aa)    
Predicted Functional Partners:
CRY2
Cryptochrome circadian regulator 2.
   
 
 0.688
BHLHE41
Basic helix-loop-helix family member e41.
    
 
 0.595
CRY1
Cryptochrome circadian regulator 1.
   
 
 0.589
NR1D2
Nuclear receptor subfamily 1 group D member 2.
   
 
 0.574
DUSP10
Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.558
NPAS4
Neuronal PAS domain protein 4.
      
 0.557
IRF1
Interferon regulatory factor.
      
 0.523
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
      
 0.507
SPEGNB
SPEG neighbor.
      
 0.504
MIGA2
Mitoguardin 2.
      
 0.501
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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