STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MALT1MALT1 paracaspase. (848 aa)    
Predicted Functional Partners:
BCL10
BCL10 immune signaling adaptor.
    
 0.999
CARD11
Caspase recruitment domain family member 11.
    
 0.998
IKBKG
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.992
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.985
CARD9
Caspase recruitment domain family member 9.
    
 0.971
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.951
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.937
CASP8
Caspase 8; Belongs to the peptidase C14A family.
    
 0.909
MAPK1
Mitogen-activated protein kinase; Belongs to the PP2C family.
    
 0.899
MAPK12
Mitogen-activated protein kinase.
    
  0.899
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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