STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSPAN5Tetraspanin. (268 aa)    
Predicted Functional Partners:
GOSR2
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
     
 0.752
STPG2
Sperm tail PG-rich repeat containing 2.
      
 0.622
TSPAN12
Tetraspanin.
      
0.619
ABCC6
ATP binding cassette subfamily C member 6.
   
 
 0.539
CD9
CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, [...]
    
 
0.532
TSPAN31
Tetraspanin 31; Belongs to the tetraspanin (TM4SF) family.
      
 0.515
CD81
Tetraspanin.
   
 
0.511
PTGFR
Prostaglandin FP receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.510
TSPAN32
Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family.
   
 
 0.499
PFDN1
Prefoldin subunit 1.
      
 0.497
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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