Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHAF1AChromatin assembly factor 1 subunit A. (959 aa)    
Predicted Functional Partners:
CHAF1B
Chromatin assembly factor 1 subunit B.
   
 
 0.984
ASF1B
Anti-silencing function 1B histone chaperone.
   
 
 0.963
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 
 0.960
ASF1A
Anti-silencing function 1A histone chaperone.
   
 
 0.937
CBX5
Chromobox 5.
   
 
 0.937
MCM2
DNA helicase; Belongs to the MCM family.
   
 
 0.838
MCM5
Minichromosome maintenance complex component 5; Belongs to the MCM family.
   
  
 0.828
MBD1
Methyl-CpG binding domain protein 1.
    
 
 0.828
POLA1
DNA polymerase.
   
 
 0.822
MCM3
DNA helicase; Belongs to the MCM family.
   
  
 0.818
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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