Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
OGG18-oxoguanine DNA glycosylase. (344 aa)    
Predicted Functional Partners:
NEIL1
Nei like DNA glycosylase 1.
     
 0.922
APEX1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
   
 0.875
POLH
DNA polymerase eta.
  
 
 0.835
NEIL2
Nei like DNA glycosylase 2.
     
 0.830
NTHL1
Nth like DNA glycosylase 1.
   
 
 0.823
XRCC1
X-ray repair cross complementing 1.
    
 
 0.813
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 
 0.810
MLH1
MutL homolog 1.
   
  
 0.755
POLI
DNA polymerase iota.
  
 
 0.754
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
   
 
  0.732
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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