PRRT3 protein (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PRRT3

Proline rich transmembrane protein 3. (982 aa)

Predicted Functional Partners:

NEDD8

0.712

UBA52

0.625

VSTM2L

0.581

RPS27A

0.566

LOC109502223

0.566

ERCC8

0.548

FCAR

0.542

POLR3A

0.540

SENP8

0.536

ZZEF1

0.507

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ERCC8	LOC109502223	ENSFCAP00000054354	ENSFCAP00000032729	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	Ubiquitin-like domain-containing protein.	0.765
ERCC8	NEDD8	ENSFCAP00000054354	ENSFCAP00000005190	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	NEDD8 ubiquitin like modifier.	0.826
ERCC8	PRRT3	ENSFCAP00000054354	ENSFCAP00000013181	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	Proline rich transmembrane protein 3.	0.548
ERCC8	RPS27A	ENSFCAP00000054354	ENSFCAP00000018695	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	Ribosomal protein S27a.	0.765
ERCC8	UBA52	ENSFCAP00000054354	ENSFCAP00000009037	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.814
FCAR	PRRT3	ENSFCAP00000007928	ENSFCAP00000013181	Ig domain-containing protein.	Proline rich transmembrane protein 3.	0.542
FCAR	VSTM2L	ENSFCAP00000007928	ENSFCAP00000057414	Ig domain-containing protein.	V-set and transmembrane domain containing 2 like.	0.482
LOC109502223	ERCC8	ENSFCAP00000032729	ENSFCAP00000054354	Ubiquitin-like domain-containing protein.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.765
LOC109502223	NEDD8	ENSFCAP00000032729	ENSFCAP00000005190	Ubiquitin-like domain-containing protein.	NEDD8 ubiquitin like modifier.	0.894
LOC109502223	PRRT3	ENSFCAP00000032729	ENSFCAP00000013181	Ubiquitin-like domain-containing protein.	Proline rich transmembrane protein 3.	0.566
LOC109502223	UBA52	ENSFCAP00000032729	ENSFCAP00000009037	Ubiquitin-like domain-containing protein.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.995
NEDD8	ERCC8	ENSFCAP00000005190	ENSFCAP00000054354	NEDD8 ubiquitin like modifier.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.826
NEDD8	LOC109502223	ENSFCAP00000005190	ENSFCAP00000032729	NEDD8 ubiquitin like modifier.	Ubiquitin-like domain-containing protein.	0.894
NEDD8	PRRT3	ENSFCAP00000005190	ENSFCAP00000013181	NEDD8 ubiquitin like modifier.	Proline rich transmembrane protein 3.	0.712
NEDD8	RPS27A	ENSFCAP00000005190	ENSFCAP00000018695	NEDD8 ubiquitin like modifier.	Ribosomal protein S27a.	0.894
NEDD8	SENP8	ENSFCAP00000005190	ENSFCAP00000000603	NEDD8 ubiquitin like modifier.	SUMO peptidase family member, NEDD8 specific.	0.996
NEDD8	UBA52	ENSFCAP00000005190	ENSFCAP00000009037	NEDD8 ubiquitin like modifier.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.936
POLR3A	PRRT3	ENSFCAP00000057302	ENSFCAP00000013181	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Proline rich transmembrane protein 3.	0.540
POLR3A	UBA52	ENSFCAP00000057302	ENSFCAP00000009037	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.452
PRRT3	ERCC8	ENSFCAP00000013181	ENSFCAP00000054354	Proline rich transmembrane protein 3.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.548