node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F10 | F2 | ENSFCAP00000013217 | ENSFCAP00000017324 | Coagulation factor X. | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | 0.988 |
F10 | F3 | ENSFCAP00000013217 | ENSFCAP00000011837 | Coagulation factor X. | Coagulation factor III, tissue factor. | 0.864 |
F10 | F5 | ENSFCAP00000013217 | ENSFCAP00000007547 | Coagulation factor X. | Coagulation factor V; Belongs to the multicopper oxidase family. | 0.987 |
F10 | F7 | ENSFCAP00000013217 | ENSFCAP00000013216 | Coagulation factor X. | Coagulation factor VII. | 0.985 |
F10 | F8 | ENSFCAP00000013217 | ENSFCAP00000053511 | Coagulation factor X. | Coagulation factor VIII; Belongs to the multicopper oxidase family. | 0.823 |
F10 | F9 | ENSFCAP00000013217 | ENSFCAP00000006767 | Coagulation factor X. | Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family. | 0.957 |
F10 | GGCX | ENSFCAP00000013217 | ENSFCAP00000033750 | Coagulation factor X. | Gamma-glutamyl carboxylase. | 0.894 |
F10 | SERPINC1 | ENSFCAP00000013217 | ENSFCAP00000013843 | Coagulation factor X. | Serpin family C member 1; Belongs to the serpin family. | 0.994 |
F10 | TFPI | ENSFCAP00000013217 | ENSFCAP00000012107 | Coagulation factor X. | Tissue factor pathway inhibitor. | 0.970 |
F10 | VWF | ENSFCAP00000013217 | ENSFCAP00000041997 | Coagulation factor X. | Uncharacterized protein. | 0.936 |
F2 | F10 | ENSFCAP00000017324 | ENSFCAP00000013217 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor X. | 0.988 |
F2 | F3 | ENSFCAP00000017324 | ENSFCAP00000011837 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor III, tissue factor. | 0.696 |
F2 | F5 | ENSFCAP00000017324 | ENSFCAP00000007547 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor V; Belongs to the multicopper oxidase family. | 0.998 |
F2 | F7 | ENSFCAP00000017324 | ENSFCAP00000013216 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor VII. | 0.801 |
F2 | F8 | ENSFCAP00000017324 | ENSFCAP00000053511 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor VIII; Belongs to the multicopper oxidase family. | 0.916 |
F2 | F9 | ENSFCAP00000017324 | ENSFCAP00000006767 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family. | 0.814 |
F2 | GGCX | ENSFCAP00000017324 | ENSFCAP00000033750 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Gamma-glutamyl carboxylase. | 0.937 |
F2 | SERPINC1 | ENSFCAP00000017324 | ENSFCAP00000013843 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Serpin family C member 1; Belongs to the serpin family. | 0.999 |
F2 | TFPI | ENSFCAP00000017324 | ENSFCAP00000012107 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Tissue factor pathway inhibitor. | 0.664 |
F2 | VWF | ENSFCAP00000017324 | ENSFCAP00000041997 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.886 |