STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUL4ACullin 4A; Belongs to the cullin family. (761 aa)    
Predicted Functional Partners:
DDB1
Damage specific DNA binding protein 1.
   
 0.999
DCAF1
DDB1 and CUL4 associated factor 1.
   
 0.998
DDB2
Damage specific DNA binding protein 2.
    
 0.984
CRBN
Cereblon.
    
 0.984
RBX1
Ring-box 1.
    
 0.980
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.978
CUL4B
Cullin 4B; Belongs to the cullin family.
  
  
0.971
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.949
DDA1
DET1 and DDB1 associated 1.
    
 0.945
DTL
Denticleless E3 ubiquitin protein ligase homolog.
    
 0.914
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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